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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f9aad25ec72fdb9e22bca785997dde194c3b54baadc1314eb3f48d78336f1d' 
  AND token = '2dKwIOPzFHzfufe8tsdeQFV4g0zJ1f04A22I9fayk/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}