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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b0c454f1ccc8ff297b9d5a7af380566fff4086b5584435f4d8148381747778f' 
  AND token = '4DXfve8fAw9OD0gk3Q8aYooeAHVYZ9UnTpSo99eq1V0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}