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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4fdf5bc22d334b7272cda0cb150a35ed4ef0c671e4ba635f07302c5ec723f8f' 
  AND token = 'J652AMsmOUEKBIWbtpf46TNzqIS/hABvbGfslTnBvtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}