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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43a2516206df31ddaf16c1a786e404ddbab4d18e2452b494aca04d161e12189' 
  AND token = 'gzcXWWarsR81i+FrMmhW+cCfxd4cxzYhuTtbAMg3zFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}