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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad353a43c4a067c348979b69859c732b0a135a6d0b2bcd6b60571458e425b6b' 
  AND token = 'F5YF55Sqzo0QMtWy5syXJmC8VjeRc6448JCJgafmTF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}