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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f825f59d64293d10bccaa77dfc430d4f54c92be8c5d4e2be4fb4114e535313a6' 
  AND token = 'vQ0nsfAHabXvmhMbSogpbwXw5f9F4RJKN/2mf0y/KFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}