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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0fe15b053ee48ee2621c31218ab67bf948711c8767700ab19fa93b01c263bcc' 
  AND token = 'oH1XXVFPUzT5bAAxwrvZRTCQj8UyKdu0BG9PmPcsy9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}