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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2cf714dc213a88fa424d97f8215215dbd89ae03c8336484f519475cae27e638' 
  AND token = '1N1DOOAR/3QiSCGljRQMPLtKa5FuKfTNk4FZEzyN6wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}