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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3cb09b822053b3201dc0b024478059ae502be2f7695b69472b28921e76d5112' 
  AND token = '9GBqupPoG8uTiedX8V6uJzV1N+abWHC7yvSXHNEd28U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}