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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb911a105b27379ad6338c21143718cc8e1f74e6106889898a0fa5d8c47d8113' 
  AND token = 'FdJ5aWr78lSEdo2UYiS9kk/31/eJeKUGjFBvBZoKKuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}