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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bddc82a4663f32adab2a0b5fa0353eb9b3d35028b6dfdb86e447aab343d843a' 
  AND token = 'XNWlSN5fSxcDS0n62Z5AxwoXNk/0uOzJ8pGd5uz7nGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}