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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dcaab6d0a59f24a51bc50ac75204b2641acd6bd8c6f2291f2ecd52e7b5b9bff' 
  AND token = 'ruLG4tO8NIPo2Vi0BSKeSToVffOjInM0mcz32YWm2d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}