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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1218c5bee1ecd2647d04105b4a595af87a91e0d6731571d306278ed55147593a' 
  AND token = 'B14ONW0WVRiRSv+8otWlStpEkPF0H2W3aPLxszzyGu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}