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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '942f0a1025406b74658bd1658675326098c0cd153a10b7883a88147e7be0593c' 
  AND token = 'b8MqsvdrDdJcTpjTI9Ve5BiyYIf4GGsxId+3WHiqr5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}