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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9b10f4df27147a688ef367548f17d5b1c6d1ab7222c9689e117a99d0aff7355' 
  AND token = 'e3f0tU9Twq09/P7foEgdRylGbqh60PDfP9irHZ0oHhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}