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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c30c15feda41332562b54b5cfcae900386ee20ca310b68485514ac77b1446e' 
  AND token = 'A22EuLjAk1KRYk/r4mRpiE1zyqiKxi7BcVW08vaMXzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}