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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52ffa74427fd7bbbeead15a43450484f7161019713308d1f7e403814e2f0980' 
  AND token = 'HiZq+2RVC8O9p9q95qz5WayD+ZPsJzyX++3lIfHkdK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}