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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b6750200ec99ca8a36944a78c9a6c9f677fc7988489dd81724365df590f051' 
  AND token = 'tSV44Qkwd/Fyb5d2d4npJtm5viGJQW8nOnyYCuIVnsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}