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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2565e4274f6db57a88a4f0992963c464107777796a6d99fa75cdad474d7f702b' 
  AND token = 'ZgaGPz3kWAFZ1Qermg19dLaiTNBVyZS1HBse+m72QKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}