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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ee28300e443bc29b80a218ff50b4e13e525e8667da6ede234e1cc207b342a8c' 
  AND token = '5PoHUK3hRyX7lU4EWztyvaqSUn7APcqlYqFivV17zho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}