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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c436e659bbec26ad5081ec87db1701c224505a780b3de2168cba1f4206d4bb3' 
  AND token = 'V9o7LJV21Ar/RkgzkD3NWjlbUhoj7kMqS3GrcAUV9R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}