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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4906c8e072c2015e505cd4a95b35b8463a9e182e7cd671f6f50f624cd37d9589' 
  AND token = 'oaaXr2ZpI3gxQE5ZIaIqk/9uJ4qfC1fqCftTLArIUcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}