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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc160831e8516b9204124a8efee0f1d12b1ffa6de5ac9ee87680c2fe4b6ed198' 
  AND token = '2ErIe2GpPlwFis7BNGOu2OgmfpBsU1XBustbPyH9GaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}