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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1e2cd5f6e310129ef7e62c8c67fa563dbe2cfe6a6c5a37ec2cd0cd5072484a4' 
  AND token = 'XmjMelCjbwby6PirN/TSNrnqC4UaWjDg0UJqBDklYmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}