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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '702546957e02c6161514b0d2dac132533e0d6f461ff75d2e4bce5f9a5f0ba650' 
  AND token = 'VwHy6DRTiRY2qrgREvVbwGvzCO3R2lJVMCg7ibxDCcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}