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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c63b81120e2100e5af1f9b79ed1e760e294b704affffd2cb8dbd03931d9b4e1f' 
  AND token = 'GAdTdeFxgg+pbPDWTWnjnr2ZES656Kpbw6GJ1+xF/xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}