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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afad68a8457939ad008c0456b6bb6041a6faf6829512c3662bf4e7e06dd4e5cb' 
  AND token = 'g6ZEGTtK89OcX8f+gDOdUXzM3x/QPHtytbZhblYgY2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}