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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c28befdb2d83068d4f832f809e80d8889717e6c5bde052a3ad2f0576027f42' 
  AND token = '+fcyrT0aVDv8bB6/p/2/lm5B3jUIl3mVr5dn0ou6b4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}