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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '759432d9b30c1aaa0993459103eb22187ba961444b2998f4f0ecff4904f3dc8b' 
  AND token = 'OdZoWD13TDi+RALxIz9nqEMP+GTEGhk1zY6kIwoWp3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}