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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '386607878f42f3f41054e413cabea913c8ebe3e9d6d42ef7b010a9a94438cc4f' 
  AND token = 'ctaTxVbuj9cRhcKXJirIe6beZkyx8VkDOhwpCkAB4lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}