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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8bb9d3290a8785d722882bfc38e6dbbfef285d35357093a71e46d4079e7445' 
  AND token = 'aApY5E1OxrPHk+3OmS/eghXA/VWrZKs5yNce3FpTncU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}