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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '142159de00a20cce9dd5ffb6e28a9cb9af7a7133e03924e9de70589d8a39f5ef' 
  AND token = 'u8QHZkO8cz2en0FFXFxCep94MMrrwUlBr7zl/RwDpww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}