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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ecd9a6e0fa3128b1014b73d84b00cfa790afbc409c27e49e376a2ad75d5f087' 
  AND token = 'AGKyH5muHOstMd5hSpns5n3wcGl7qUrO+OO3G2uHDk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}