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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc1748a2854a6a3082f9e545acb8ce1f23980e995923af19b1246131fde47526' 
  AND token = 'ZiwGOLDQGt2s/E8b7/MRZq4UJxXXkj8MWalMN+T2nUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}