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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '981ec9aeb464b47fd849ce3f1a94d55a1fce5a0c923ffbb21e5068062fd98b43' 
  AND token = 'UGSQfqv1T1sLLwkn2pMEyxpoPnmQMM1WRQNEszgV9SY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}