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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2143e32e9726ef903492f108d92693d491d83171bc2bd0671209d38a613b2a78' 
  AND token = 'FH2XmYv/ldZPnG96N2h0C66tHAeTrWG0POSvu/CkBIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}