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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8372d5709bf942741f5b92f7bb2563e91e9f78f9b466e6b0760c17d587e4c915' 
  AND token = '73lUrnS0dlY8Fkt/7XhpDpD8jIt3Yi9GyUotb/q3G+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}