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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309c9b4d8b2526508ff1401e00ca969fbf59166db29c0af7c7ff87f1a3f6627c' 
  AND token = 'K7hj+RRna8WaYTyTgp+1kCUKIVPKvZj31XNfZi8nb7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}