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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adea7ccf45d5f9b1687d33a88ac77cf0f62e8f04013f76f30df434cac36cd38c' 
  AND token = 'gbkpdt2EjbCGexDGfOhhlkKKlCr7qJOXlGkT1P9UBYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}