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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a2b73fe4e992004b2c740d7457c6eb4c8051ef3ea5ed43827ce3652c5d660e0' 
  AND token = 'UA5N+vpC3ufl/tppWVYg1d5KGd1JC+cYpLjwLqL4ado=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}