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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341631cb0a46633f8e7c1d07acc68f75b28330e7b7e8fb069786d9432524c322' 
  AND token = '10SPWEzbDv0ixBrSSdPvcKULcXOF5LYL/Yz1VQBl89k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}