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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb4d02423e26a0fe3b46a07ac7065edd9fd90f8521b0d1b91f6ec4b2414d912' 
  AND token = 'h172CDSUklxqya0IUctFmICL/63QB3GgBssLTDhaKX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}