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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acc8de69851ec77e51ceced28509b9411bb8c08edbf33f8fca7cf474dca43b3b' 
  AND token = 'EvbXr3ks70a/WUMhGl4aY3aRDqjzd+yRFuBxWgqzCp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}