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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e43c2c9ea2d3d128f8dde9706f2dfa01c14cebe607df10ae93fed758b3bf7d' 
  AND token = 'lX5Q/vrf0FQnXv/brt/FrpmKqSSaSymtnh6+ziaz/WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}