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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d292385db89289c5c94f73f467646f138609eb67075440bd234b4d04d0ff6f' 
  AND token = '9wxfEUI7fl5BB5xYQ632+/8IouRF7yCbrWyyLJagUX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}