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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d6736cff82c6ba56b8ee50c673571b4ae2a27aa54cb981c80156848ead72065' 
  AND token = 'YTnUCO2LgSwPHVvEbY75Hose/tzbSRIPDFOvvhbL3m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}