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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4a26263206c854a017108b69b0202f37f5e46e3330e521a271b9715e0017b86' 
  AND token = 'QjargSZVUar3ZeOgWnzsKd8Qa6ek+V3urUwq4kKkOqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}