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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4662d362f7aabe8154a119769fbc904958dec31c45d1190c3fba65d7a5fd3181' 
  AND token = 'Z26FyoCN37ifs9rqdbIhhCSEZeE4jxK97AiYwElUeEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}