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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e307c0e7970d02cd774e8350e37566063b56d868ed2c3c3152844687fdfca53' 
  AND token = '8FWoPR05rJsM7fI6zTLUp8zExT6Fh+DUxTHDB1Erqd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}