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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b374b2858162aca53be24e28ebc2d76b97b86c23716b15d1a0a1b2ddac01d10a' 
  AND token = '1dYLetl+y3PebA+/bjfw/6VS9LVUCgwzH6uYvU7oJv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}